@inproceedings {1653, title = {Multi-voxel algorithm for quantitative bi-exponential MRI T1 estimation}, booktitle = {SPIE Medical Imaging}, volume = {9784}, year = {2016}, pages = {978402}, address = {San Diego, California, United States of America}, abstract = {In this work, we propose a joint multi-voxel bi-exponential estimator (JMBE) for quantitative bi-exponential T1 estimation in magnetic resonance imaging, to account for partial volume effects and to yield more accurate results compared to single-voxel bi-exponential estimators (SBEs). Using a numerical brain phantom with voxels containing two tissues, the minimal signal-to-noise ratio (SNR) needed to estimate both T1 values with sufficient accuracy was investigated. Compared to the SBE, and for clinically achievable single-voxel SNRs, the JMBE yields accurate T1 estimates if four or more neighboring voxels are used in the joint estimation framework, in which case it is also efficient.}, doi = {http://dx.doi.org/10.1117/12.2216831}, author = {Piet Bladt and Gwendolyn Van Steenkiste and Gabriel Ramos-Llord{\'e}n and Arnold Jan den Dekker and Jan Sijbers} }