@mastersthesis {2069, title = {Accurate and precise perfusion parameter estimation in pseudo-continuous arterial spin labeling MRI}, volume = {PhD in Sciences/Physics}, year = {2020}, type = {PhD thesis}, author = {Piet Bladt} } @article {1956, title = {The costs and benefits of estimating T1 of tissue alongside cerebral blood flow and arterial transit time in pseudo-continuous arterial spin labeling}, journal = {NMR in Biomedicine}, volume = {33}, year = {2020}, pages = {1-17}, doi = {https://doi.org/10.1002/nbm.4182}, author = {Piet Bladt and Arnold Jan den Dekker and Clement, Patricia and Eric Achten and Jan Sijbers} } @article {2051, title = {Supporting measurements or more averages? How to quantify cerebral blood flow most reliably in 5 minutes by arterial spin labeling}, journal = {Magnetic Resonance in Medicine}, volume = {84}, year = {2020}, pages = {2523-2536}, doi = {10.1002/mrm.28314}, author = {Piet Bladt and M.J.P van Osch and Clement, Patricia and Eric Achten and Jan Sijbers and Arnold Jan den Dekker} } @conference {1993, title = {Beyond the consensus: is sacrificing part of the PCASL scan time for measurement of labeling efficiency and T1 of blood beneficial?}, year = {2019}, author = {Piet Bladt and M.J.P van Osch and Eric Achten and Arnold Jan den Dekker and Jan Sijbers} } @conference {1994, title = {Beyond the consensus: should measurement of T1 of blood and labeling efficiency be included and should a single- or multi-PLD protocol be used in a five-minute protocol for PCASL?}, year = {2019}, author = {Piet Bladt and M.J.P van Osch and Eric Achten and Arnold Jan den Dekker and Jan Sijbers} } @conference {1992, title = {Beyond the consensus: what to include when 5 minutes are available for perfusion imaging by PCASL?}, year = {2019}, author = {Piet Bladt and M.J.P van Osch and Eric Achten and Arnold Jan den Dekker and Jan Sijbers} } @conference {1995, title = {Absolute CBF quantification in multi-time point ASL: the T1 issue}, year = {2018}, author = {Piet Bladt and Arnold Jan den Dekker and Clement, Patricia and Eric Achten and Jan Sijbers} } @article {1843, title = {Modeling brain dynamics in brain tumor patients using The Virtual Brain}, journal = {eNeuro}, year = {2018}, abstract = {Presurgical planning for brain tumor resection aims at delineating eloquent tissue in the vicinity of the lesion to spare during surgery. To this end, non-invasive neuroimaging techniques such as functional MRI and diffusion weighted imaging fiber tracking are currently employed. However, taking into account this information is often still insufficient, as the complex non-linear dynamics of the brain impede straightforward prediction of functional outcome after surgical intervention. Large-scale brain network modeling carries the potential to bridge this gap by integrating neuroimaging data with biophysically based models to predict collective brain dynamics. As a first step in this direction, an appropriate computational model has to be selected, after which suitable model parameter values have to be determined. To this end, we simulated large-scale brain dynamics in 25 brain tumor patients and 11 control subjects using The Virtual Brain, an open-source neuroinformatics platform. Local and global model parameters of the Reduced Wong-Wang model were individually optimized and compared between brain tumor patients and control subjects. In addition, the relationship between model parameters and structural network topology and cognitive performance was assessed. Results showed (1) significantly improved prediction accuracy of individual functional connectivity when using individually optimized model parameters; (2) local model parameters can differentiate between regions directly affected by a tumor, regions distant from a tumor, and regions in a healthy brain; and (3) interesting associations between individually optimized model parameters and structural network topology and cognitive performance.}, doi = {10.1101/265637}, url = {https://www.biorxiv.org/content/early/2018/05/07/265637}, author = {Aerts, Hannelore and Schirner, Michael and Ben Jeurissen and Van Roost, Dirk and Eric Achten and Ritter, Petra and Marinazzo, Daniele} } @conference {1996, title = {Maximizing precision in PCASL MRI using an optimized sampling strategy}, year = {2017}, author = {Piet Bladt and Arnold Jan den Dekker and Clement, Patricia and Eric Achten and Jan Sijbers} } @conference {1997, title = {Optimal sampling strategy for pseudo-continuous arterial spin labeling MRI}, year = {2017}, author = {Piet Bladt and Arnold Jan den Dekker and Clement, Patricia and Eric Achten and Jan Sijbers} } @conference {1826, title = {Super-resolution multi-PLD PCASL: a simulation study}, volume = {30 (Suppl. 1)}, number = {S396}, year = {2017}, publisher = {Magn Reson Mater Phy}, abstract = {Cerebral blood flow (CBF) can be estimated non-invasively with arterial spin labeling (ASL). Multi-post-labeling-delay (PLD) pseudo-continuous ASL (PCASL) allows for accurate CBF estimation by sampling the dynamic perfusion signal at different PLDs and fitting a model to the perfusion data. Unfortunately, ASL difference images have a low SNR. Therefore, CBF estimation in multi-PLD PCASL is imprecise, unless a large number of images is acquired (long scan time) or spatial resolution is lowered significantly. It has been shown that model-based super-resolution reconstruction (SRR) techniques can improve the trade-off between SNR, spatial resolution and acquisition time. The results presented in this work show the promising potential of SRR ASL to outperform conventional ASL readout schemes in terms of achievable precision of HR perfusion measurements in a given acquisition time.}, doi = {10.1007/s10334-017-0634-z}, author = {Piet Bladt and Quinten Beirinckx and Gwendolyn Van Steenkiste and Ben Jeurissen and Eric Achten and Arnold Jan den Dekker and Jan Sijbers} } @article {dpootajdendekAchtenmverhoyejsijbers2010, title = {Optimal experimental design for Diffusion Kurtosis Imaging}, journal = {IEEE Transactions on Medical Imaging}, volume = {29}, number = {3}, year = {2010}, pages = {819-829}, doi = {http://dx.doi.org/10.1109/TMI.2009.2037915}, author = {Dirk H J Poot and Arnold Jan den Dekker and Eric Achten and Marleen Verhoye and Jan Sijbers} } @inproceedings {DelputtealeemansFieremansDeeneDAsselerLemahieuAchtenjsijbersWalle2005, title = {Density Regularized Fiber Tractography of the Brain White Matter using Diffusion Tensor MRI}, booktitle = {13th Scientific Meeting - International Society for Magnetic Resonance in Medicine}, year = {2005}, pages = {1309}, address = {Miami, USA}, author = {S. Delputte and Alexander Leemans and Els Fieremans and Y. De Deene and Y. D{\textquoteright}Asseler and I. Lemahieu and Eric Achten and Jan Sijbers and R. Van de Walle} }