@article {forde2015structural,
	title = {Structural brain network analysis in families multiply affected with bipolar I disorder},
	journal = {Psychiatry Research: Neuroimaging},
	volume = {234},
	number = {1},
	year = {2015},
	pages = {44{\textendash}51},
	publisher = {Elsevier},
	author = {Forde, Natalie J and O{\textquoteright}Donoghue, Stefani and Scanlon, Cathy and Louise Emsell and Chaddock, Chris and Alexander Leemans and Ben Jeurissen and Gareth J. Barker and Dara M. Cannon and Murray, Robin M and others}
}
@conference {1554,
	title = {Structural brain network analysis in families multiply affected with bipolar 1 disorder},
	year = {2014},
	address = {Athens, Greece},
	author = {Forde, Natalie J and Scanlon, Cathy and Louise Emsell and O{\textquoteright}Donoghue, S and Chaddock, Chris and Alexander Leemans and Ben Jeurissen and Dara M. Cannon and Murray, R M and Colm McDonald}
}
@article {1546,
	title = {Structural neuroimaging correlates of allelic variation of the BDNF val66met polymorphism.},
	journal = {NeuroImage},
	volume = {90},
	year = {2014},
	month = {2014 Apr 15},
	pages = {280-9},
	abstract = {BACKGROUND: The brain-derived neurotrophic factor (BDNF) val66met polymorphism is associated with altered activity dependent secretion of BDNF and a variable influence on brain morphology and cognition. Although a met-dose effect is generally assumed, to date the paucity of met-homozygotes have limited our understanding of the role of the met-allele on brain structure.

METHODS: To investigate this phenomenon, we recruited sixty normal healthy subjects, twenty in each genotypic group (val/val, val/met and met/met). Global and local morphology were assessed using voxel based morphometry and surface reconstruction methods. White matter organisation was also investigated using tract-based spatial statistics and constrained spherical deconvolution tractography.

RESULTS: Morphological analysis revealed an "inverted-U" shaped profile of cortical changes, with val/met heterozygotes most different relative to the two homozygous groups. These results were evident at a global and local level as well as in tractography analysis of white matter fibre bundles.

CONCLUSION: In contrast to our expectations, we found no evidence of a linear met-dose effect on brain structure, rather our results support the view that the heterozygotic BDNF val66met genotype is associated with cortical morphology that is more distinct from the BDNF val66met homozygotes. These results may prove significant in furthering our understanding of the role of the BDNF met-allele in disorders such as Alzheimer{\textquoteright}s disease and depression.},
	keywords = {Adolescent, Adult, Alleles, Brain, Brain-Derived Neurotrophic Factor, diffusion tensor imaging, Female, Genotype, Heterozygote, Homozygote, Humans, Image Processing, Computer-Assisted, Male, Middle Aged, Polymorphism, Single Nucleotide, Young Adult},
	issn = {1095-9572},
	doi = {10.1016/j.neuroimage.2013.12.050},
	author = {Forde, Natalie J and Ronan, Lisa and Suckling, John and Scanlon, Cathy and Neary, Simon and Holleran, Laurena and Alexander Leemans and Tait, Roger and Rua, Catarina and Fletcher, Paul C and Ben Jeurissen and Dodds, Chris M and Miller, Sam R and Bullmore, Edward T and Colm McDonald and Nathan, Pradeep J and Dara M. Cannon}
}
@article {1368,
	title = {Limbic and callosal white matter changes in euthymic bipolar I disorder: an advanced diffusion MRI tractography study},
	journal = {Biologicial Psychiatry},
	volume = {73},
	year = {2013},
	pages = {194-201},
	doi = {http://dx.doi.org/10.1016/j.biopsych.2012.09.023},
	author = {Louise Emsell and Alexander Leemans and Camilla Langan and Wim Van Hecke and Gareth J. Barker and Peter McCarthy and Ben Jeurissen and Jan Sijbers and Stefan Sunaert and Dara M. Cannon and Colm McDonald}
}
@conference {1553,
	title = {White Matter Tract Deficits in Schizophrenia},
	volume = {7},
	year = {2011},
	address = {Dublin, Ireland},
	author = {Forde, Natalie J and Ellison-Wright, I and Nathan, Pradeep J and Zaman, R and Dudas, R and Agius, M and Fernandez-Egea, E and Alexander Leemans and Ben Jeurissen and Scanlon, Cathy and Colm McDonald and Dara M. Cannon}
}
