@article {wvheckeNagelsaleemansVandervlietjsijbersParizel2010,
	title = {Correlation of cognitive dysfunction and diffusion tensor MRI measures in patients with mild and moderate multiple sclerosis},
	journal = {Journal of magnetic resonance imaging},
	volume = {31},
	number = {6},
	year = {2010},
	month = {May},
	pages = {1492-1498},
	author = {Wim Van Hecke and Guy Nagels and Alexander Leemans and Everhard Vandervliet and Jan Sijbers and Paul M Parizel}
}
@article {1376,
	title = {A diffusion tensor imaging group study of the spinal cord in multiple sclerosis patients with and without T2 spinal cord lesions.},
	journal = {Journal of magnetic resonance imaging : JMRI},
	volume = {30},
	year = {2009},
	month = {2009 Jul},
	pages = {25-34},
	abstract = {PURPOSE: To examine the T(2)-normal appearing spinal cord of patients with multiple sclerosis (MS) using diffusion tensor imaging.

MATERIALS AND METHODS: Diffusion tensor images of the spinal cord were acquired from 21 healthy subjects, 11 MS patients with spinal cord lesions, and 10 MS patients without spinal cord lesions on the T(2)-weighted MR images. Different diffusion measures were evaluated using both a region of interest (ROI) -based and a diffusion tensor tractography-based segmentation approach.

RESULTS: It was observed that the FA, the transverse diffusivity lambda(perpendicular), and the ratio of the longitudinal and transverse diffusivities (lambda(parallel)/lambda (perpendicular)) were significantly lower in the spinal cord of MS patients with spinal cord lesions compared with the control subjects using both the ROI method (P = 0.014, P = 0.028, and P = 0.039, respectively) and the tractography-based approach (P = 0.006, P = 0.037, and P = 0.012, respectively). For both image analysis methods, the FA and the lambda (parallel)/lambda (perpendicular) values were significantly different between the control group and the MS patient group without T(2) spinal cord lesions (P = 0.013).

CONCLUSION: Our results suggest that the spinal cord may still be affected by MS, even when lesions are not detected on a conventional MR scan. In addition, we demonstrated that diffusion tensor tractography is a robust tool to analyze the spinal cord of MS patients.},
	keywords = {Adult, Analysis of Variance, anisotropy, Diffusion Magnetic Resonance Imaging, Female, Humans, Image Processing, Computer-Assisted, Male, Multiple Sclerosis, Observer Variation, Reproducibility of Results, Spinal Cord, Spinal Cord Diseases, Thoracic Vertebrae},
	issn = {1053-1807},
	doi = {10.1002/jmri.21817},
	author = {Wim Van Hecke and Guy Nagels and Emonds, Griet and Alexander Leemans and Jan Sijbers and van Goethem, Johan and Paul M Parizel}
}
@inproceedings {VandervlietNagelsHeineckewvheckealeemansjsijbersParizel2006,
	title = {On the cause and mechanisms of the negative BOLD response in fMRI},
	booktitle = {23rd Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology},
	year = {2006},
	pages = {308},
	address = {Warsaw, Poland},
	author = {Everhard Vandervliet and Guy Nagels and A. Heinecke and Wim Van Hecke and Alexander Leemans and Jan Sijbers and Paul M Parizel}
}
@inproceedings {NagelsVandervlietwvheckeEngelborghshoogheCrasParizelDeyn2006,
	title = {fMRI during PASAT and PVSAT in mild MS, moderate MS and normal volunteers.},
	booktitle = {22nd Congress of the European Committee for},
	year = {2006},
	address = {Madrid, Spain},
	author = {Guy Nagels and Everhard Vandervliet and Wim Van Hecke and Sebastiaan Engelborghs and M.B. D hooghe and P. Cras and Paul M Parizel and P.P. De Deyn}
}
@inproceedings {MichielsjsijbersEelenmverhoyeDHoogheNagelsDeynavdlinde1999,
	title = {Simultaneous EEG and MRI in an animal model for generalized epilepsy induced in the MRI instrument},
	booktitle = {Third Meeting of the Belgian Society for Neuroscience},
	number = {25},
	year = {1999},
	month = {May},
	address = {Brussels, Belgium},
	author = {I. Michiels and Jan Sijbers and J. Eelen and Marleen Verhoye and R. Dhooghe and Guy Nagels and P.P. De Deyn and Annemie Van Der Linden}
}
@inproceedings {MichielsjsijbersEelenmverhoyeDHoogheNagelsDeynavdlinde1999,
	title = {Simultaneous EEG and MRI in an animal model for generalized epilepsy induced in the MRI instrument},
	booktitle = {16th annual meeting: Magnetic Resonance Materials in Physics, Biology, and Medicine},
	year = {1999},
	month = {September},
	address = {Sevilla, Spain},
	author = {I. Michiels and Jan Sijbers and J. Eelen and Marleen Verhoye and R. Dhooghe and Guy Nagels and P.P. De Deyn and Annemie Van Der Linden}
}
