@article {1718,
	title = {High angular resolution diffusion-weighted imaging in mild traumatic brain injury},
	journal = {NeuroImage: Clinical},
	volume = {13},
	year = {2017},
	month = {11/2016},
	pages = {174 - 180},
	abstract = {We sought to investigate white matter abnormalities in mild traumatic brain injury (mTBI) using diffusion-weighted magnetic resonance imaging (DW-MRI). We applied a global approach based on tract-based spatial statistics skeleton as well as constrained spherical deconvolution tractography. DW-MRI was performed on 102 patients with mTBI within two months post-injury and 30 control subjects. A robust global approach considering only the voxels with a single-fiber configuration was used in addition to global analysis of the tract skeleton and probabilistic whole-brain tractography. In addition, we assessed whether the microstructural parameters correlated with age, time from injury, patient{\textquoteright}s outcome and white matter \{MRI\} hyperintensities. We found that whole-brain global approach restricted to single-fiber voxels showed significantly decreased fractional anisotropy (FA) (p = 0.002) and increased radial diffusivity (p = 0.011) in patients with mTBI compared with controls. The results restricted to single-fiber voxels were more significant and reproducible than those with the complete tract skeleton or the whole-brain tractography. \{FA\} correlated with patient outcomes, white matter hyperintensities and age. No correlation was observed between \{FA\} and time of scan post-injury. In conclusion, the global approach could be a promising imaging biomarker to detect white matter abnormalities following traumatic brain injury.},
	keywords = {Diffusion-weighted magnetic resonance imaging, Global approach, Magnetic Resonance Imaging, probabilistic tractography, Traumatic brain injury},
	issn = {2213-1582},
	doi = {http://dx.doi.org/10.1016/j.nicl.2016.11.016},
	url = {http://www.sciencedirect.com/science/article/pii/S2213158216302248},
	author = {Mohammadian, Mehrbod and Timo Roine and Jussi Hirvonen and Timo Kurki and Henna Ala-Sepp{\"a}l{\"a} and Janek Frantz{\'e}n and Ari Katila and Anna Kyll{\"o}nen and Henna-Riikka Maanp{\"a}{\"a} and Jussi Posti and Riikka Takala and Jussi Tallus and Olli Tenovuo}
}
@inproceedings {7351386,
	title = {Simultaneous motion correction and T1 estimation in quantitative T1 mapping: An ML restoration approach},
	booktitle = {2015 IEEE International Conference on Image Processing (ICIP)},
	year = {2015},
	month = {Sept},
	pages = {3160-3164},
	keywords = {alignment, Approximation methods, biomedical MRI, image restoration, interpolation effect, Magnetic Resonance Imaging, maximum likelihood approach, maximum likelihood estimation, medical image processing, ML approach, ML restoration approach, motion estimation, motion model parameters, quantitative T1 mapping, registration, relaxometry, Rician channels, Signal to noise ratio, simultaneous motion correction, Standards, T1 estimation, T1 mapping, T1-weighted images, tissue spin-lattice relaxation time, voxel-wise estimation},
	doi = {10.1109/ICIP.2015.7351386},
	author = {Gabriel Ramos-Llord{\'e}n and Arnold Jan den Dekker and Gwendolyn Van Steenkiste and Johan Van Audekerke and Marleen Verhoye and Jan Sijbers}
}
@mastersthesis {1337,
	title = {Improved analysis of brain connectivity using high angular resolution diffusion MRI},
	volume = {PhD in Sciences},
	year = {2012},
	month = {03/2012},
	pages = {208},
	school = {University of Antwerp},
	type = {PhD thesis},
	keywords = {complex WM architecture, constrained spherical deconvolution, crossing fibers, CSD, Diffusion MRI, diffusion tensor imaging, DTI, HARDI, high angular resolution diffusion imaging, Magnetic Resonance Imaging, MRI, probabilistic tractography, Spherical deconvolution, Tractography, white matter, WM},
	author = {Ben Jeurissen}
}
@article {1438,
	title = {Nonlocal maximum likelihood estimation method for denoising multiple-coil magnetic resonance images.},
	journal = {Magnetic resonance imaging},
	volume = {30},
	year = {2012},
	month = {2012 Dec},
	pages = {1512-8},
	abstract = {Effective denoising is vital for proper analysis and accurate quantitative measurements from magnetic resonance (MR) images. Even though many methods were proposed to denoise MR images, only few deal with the estimation of true signal from MR images acquired with phased-array coils. If the magnitude data from phased array coils are reconstructed as the root sum of squares, in the absence of noise correlations and subsampling, the data is assumed to follow a non central-χ distribution. However, when the k-space is subsampled to increase the acquisition speed (as in GRAPPA like methods), noise becomes spatially varying. In this note, we propose a method to denoise multiple-coil acquired MR images. Both the non central-χ distribution and the spatially varying nature of the noise is taken into account in the proposed method. Experiments were conducted on both simulated and real data sets to validate and to demonstrate the effectiveness of the proposed method.},
	keywords = {Algorithms, Animals, Brain, Brain Mapping, Computer Simulation, Fourier Analysis, Image Processing, Computer-Assisted, Likelihood Functions, Magnetic Resonance Imaging, Mice, Models, Statistical, Normal Distribution, Signal-To-Noise Ratio, Stochastic Processes},
	issn = {1873-5894},
	doi = {10.1016/j.mri.2012.04.021},
	author = {Jeny Rajan and Jelle Veraart and Johan Van Audekerke and Marleen Verhoye and Jan Sijbers}
}
@article {1479,
	title = {Morphologic and functional changes in the unilateral 6-hydroxydopamine lesion rat model for Parkinson{\textquoteright}s disease discerned with microSPECT and quantitative MRI.},
	journal = {Magnetic Resonance Materials in Physics, Biology and Medicine},
	volume = {23},
	year = {2010},
	month = {04/2010},
	pages = {65-75},
	abstract = {OBJECT: In the present study, we aimed to evaluate the impact of neurodegeneration of the nigrostriatal tract in a rodent model of Parkinson{\textquoteright}s disease on the different MR contrasts (T(2), T(1), CBF and CBV) measured in the striatum.

MATERIAL AND METHODS: Animals were injected with 6-hydroxydopamine (6OHDA) in the substantia nigra resulting in massive loss of nigrostriatal neurons and hence dopamine depletion in the ipsilateral striatum. Using 7T MRI imaging, we have quantified T(2), T(1), CBF and CBV in the striata of 6OHDA and control rats. To validate the lesion size, behavioral testing, dopamine transporter muSPECT and tyrosine hydroxylase staining were performed.

RESULTS: No significant differences were demonstrated in the absolute MRI values between 6OHDA animals and controls; however, 6OHDA animals showed significant striatal asymmetry for all MRI parameters in contrast to controls.

CONCLUSIONS: These PD-related asymmetry ratios might be the result of counteracting changes in both intact and affected striatum and allowed us to diagnose PD lesions. As lateralization is known to occur also in PD patients and might be expected in transgenic PD models as well, we propose that MR-derived asymmetry ratios in the striatum might be a useful tool for in vivo phenotyping of animal models of PD.},
	keywords = {Animals, Corpus Striatum, Disease Models, Animal, Female, Magnetic Resonance Imaging, Oxidopamine, Parkinsonian Disorders, Positron-Emission Tomography, Rats, Rats, Wistar, Reproducibility of Results, Sensitivity and Specificity},
	issn = {1352-8661},
	doi = {10.1007/s10334-010-0198-7},
	author = {N. Van Camp and Vreys, Ruth and Koen Van Laere and E. Lauwers and Dirk Beque and Marleen Verhoye and Casteels, Cindy and Alfons Verbruggen and Zeger Debyser and Mortelmans, Luc and Jan Sijbers and Johan Nuyts and Veerle Baekelandt and Annemie Van Der Linden}
}
@article {1189,
	title = {Noise measurement from magnitude MRI using local estimates of variance and skewness.},
	journal = {Physics in medicine and biology},
	volume = {55},
	year = {2010},
	month = {2010 Aug 21},
	pages = {N441-9},
	abstract = {In this note, we address the estimation of the noise level in magnitude magnetic resonance (MR) images in the absence of background data. Most of the methods proposed earlier exploit the Rayleigh distributed background region in MR images to estimate the noise level. These methods, however, cannot be used for images where no background information is available. In this note, we propose two different approaches for noise level estimation in the absence of the image background. The first method is based on the local estimation of the noise variance using maximum likelihood estimation and the second method is based on the local estimation of the skewness of the magnitude data distribution. Experimental results on synthetic and real MR image datasets show that the proposed estimators accurately estimate the noise level in a magnitude MR image, even without background data.},
	keywords = {Algorithms, Artifacts, Brain, Data Interpretation, Statistical, Fourier Analysis, Humans, Image Processing, Computer-Assisted, Likelihood Functions, Magnetic Resonance Imaging, Models, Statistical, Myocardium, Normal Distribution, Reproducibility of Results},
	issn = {1361-6560},
	doi = {10.1088/0031-9155/55/16/N02},
	author = {Jeny Rajan and Dirk H J Poot and Juntu, Jaber and Jan Sijbers}
}
