Magnetic Resonance Imaging

Magnetic resonance imaging and derived modalities.

Population-averaged diffusion tensor imaging atlas of the Sprague Dawley rat brain

Rats are widely used in experimental neurobiological research, and rat brain atlases are important resources for identifying brain regions in the context of experimental microsurgery, tissue sampling, and neuroimaging, as well as comparison of findings across experiments. Currently, most available rat brain atlases are constructed from histological material derived from single specimens, and provide two-dimensional or threedimensional (3D) outlines of diverse brain regions and fiber tracts.

Denoising of DKI images: effect on feasibility and accuracy of kurtosis parameters

Kudzinava, M., J. Rajan, and J. Sijbers, "Denoising of DKI images: effect on feasibility and accuracy of kurtosis parameters", ESMRMB, European Society for Magnetic Resonance in Medicine and Biology, 28th Annual Scientific Meeting, Leipzig, Germany, pp. 236, October, 2011.

Quantification of brain connectivity using Diffusion Weighted MRI

Diffusion Weighted (DW) MRI is a unique and noninvasive method to characterize tissue microstructure, based on the random thermal motion of water molecules. Of particular interest is its potential for inferring the orientation of the coherently oriented fiber bundles within brain white matter tissue, as this opens up the possibility of investigating brain connectivity in vivo using so-called fiber-tracking algorithms. This relatively new technique is becoming a valuable diagnostic tool for a large number of neuropathological diseases.


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