Diffusion time dependence in the mid-time regime: a simulation study using PGSE.

TitleDiffusion time dependence in the mid-time regime: a simulation study using PGSE.
Publication TypeConference Abstract
Year of Publication2019
AuthorsBuikema, A. E., A J. den Dekker, and J. Sijbers
Conference Name27th Annual Meeting of the ISMRM
Number3572
Place PublishedMontreal, Canada
Abstract

The purpose of this work is to study the effect of varying the diffusion time on the estimation of the parameters of the two-compartment diffusion tensor model in the mid-time regime. Simulation results show that the precision of the diffusion time-dependent compartmental parameter estimates increases when a variable echo time acquisition scheme is used. At low SNR, however, including diffusion time-dependence may lead to a high bias and variance compared to the more conventional non diffusion time-dependent model.