An educational presentation on accurate and precise MRI relaxometry: the often disregarded but critical role of statistical parameter estimation

TitleAn educational presentation on accurate and precise MRI relaxometry: the often disregarded but critical role of statistical parameter estimation
Publication TypeConference Abstract
Year of Publication2018
AuthorsG. Ramos-Llordén, Q. Beirinckx, A J. den Dekker, and J. Sijbers
Conference Name10th Annual Meeting of the ISMRM Benelux Chapter
Place PublishedAntwerp, Belgium
Abstract

MRI relaxometry holds the promise of providing biomarkers for monitoring, staging and follow up of diseases. Imperative to meet minimum standards for objective, reproducible, and reliable biomarkers is the need for accurate, precise, quantitative parameters maps, such as T1 or T2. While unrealistic physical modelling is often argued as the main cause of lack of accuracy, little effort has been made on discussing the impact that inadequate parameter estimation methods have on the accuracy and precision of MRI relaxometry techniques. This educational poster attempts to introduce young MR students/researchers into the basics of modern statistical parameter estimation theory, and its application for accurate and precise relaxometry.